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PROJECTS
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Traumatic Brain Injury
We are investigating the molecular mechanism by which mechanical injury triggers myelin breakdown in the brain white matter
Charcot-Marie-Tooth 4B
Mutation in Mtmr2 gene causes CMT4B in human that affects the myelin in the PNS. We are studying the signaling function of Mtrm2 in regulating PNS myelination.
Stemness of Schwann cell
Schwann cell is one of the few cell types in adult that are capable of reverting back to the immature state. We investigate mechanisms underlying the process
Developmental Myelination
Myelination is regulated by inter-cellular signaling between axon and myelin forming glial cells. We are interested in understanding the molecular nature of the signaling that generate myelin.
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